REI Chief Executive Jerry Stritzke Resigns After Investigation into Undisclosed Relationship

The chief executive and president of Recreational Equipment, Inc., Jerry Stritzke, abruptly resigned Tuesday, REI announced in a statement. The company’s board accepted Stritzke’s resignation “following an investigation into the facts and circumstances surrounding a personal and consensual relationship between the REI CEO and the leader of another organization in the outdoor industry.” The investigation, which found no evidence of financial misconduct, was conducted by an external law firm and overseen by REI’s board of directors.

The company announced that Eric Artz, REI’s executive vice president and chief operating officer, will take on the role of interim CEO effective immediately. In an open letter to REI employees, REI board chair Steve Hooper praised Stritzke’s drive and innovative contributions to the company since taking over as president in October 2013. “Jerry has been an excellent CEO for REI and together, all of you have delivered outstanding results for the co-op during remarkably challenging times in retail,” Hooper wrote, adding, “The co-op is stronger today than when Jerry joined.”

Kent, Wash.-based REI was founded in 1938, an early pioneer in outdoor retail that now has 147 stores in 36 states. The company has been repeatedly ranked by Fortune as a best place to work, and measures such as REI’s Black Friday closures and million-dollar investments in initiatives that demonstrate the relationship between being outdoors and good health are often cited as evidence of its progressive workplace culture at the member-owned cooperative.

Fortune

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Jussie Smollett Hate Crime Investigation Update — Chicago Police Are Expanding Their Search, Unable to Find Video or Photos of Assailants

The Chicago Police Department has issued a statement with an update on their investigation into Jussie Smollett’s racist and homophobic attack. 

The FBI has taken over the investigation related to the threatening letter Jussie received last week, but as far as the actual attack itself police have been canvassing the area looking for surveillance footage.

TMZ reports that police visited a Target store near where the incident happened and they were able to retrieve some footage. A source says the footage shows just one person — presumably Jussie — walking down the street.

Anthony Guglielmi, Chief Communications Officer, tweeted that the department is expanding its search radius after being unable to find video or photos of the alleged attackers or any vehicles.

We’ll keep you updated as the investigation unfolds.

The post Jussie Smollett Hate Crime Investigation Update — Chicago Police Are Expanding Their Search, Unable to Find Video or Photos of Assailants appeared first on lovebscott – celebrity news.

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The Debrief: Russia investigation, Venezuela crisis, dangerous cold front| ABC News

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http://www.acrx.org -As millions of Americans strive to deal with the economic downturn,loss of jobs,foreclosures,high cost of gas,and the rising cost of prescription drug cost. Charles Myrick ,the President of American Consultants Rx, announced the re-release of the American Consultants Rx community service project which consist of millions of free discount prescription cards being donated to thousands of not for profits,hospitals,schools,churches,etc. in an effort to assist the uninsured,under insured,and seniors deal with the high cost of prescription drugs.-American Consultants Rx -Pharmacy Discount Network News

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Democrats demand investigation after report that Trump ordered Michael Cohen to lie to Congress

Democratic leaders reacted with fury to a report from BuzzFeed News that President Trump directed Michael Cohen to lie under oath about his business interests in Russia during the campaign.
Politics

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http://www.acrx.org -As millions of Americans strive to deal with the economic downturn,loss of jobs,foreclosures,high cost of gas,and the rising cost of prescription drug cost. Charles Myrick ,the President of American Consultants Rx, announced the re-release of the American Consultants Rx community service project which consist of millions of free discount prescription cards being donated to thousands of not for profits,hospitals,schools,churches,etc. in an effort to assist the uninsured,under insured,and seniors deal with the high cost of prescription drugs.-American Consultants Rx -Pharmacy Discount Network News

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Mueller confirms Kilimnik a focus of grand jury investigation

Former Trump campaign chairman Paul Manafort spoke to a federal grand jury last fall about his communications with Konstantin Kilimnik, including regarding an in-person meeting with the Russian associate and an email with him, special counsel Robert Mueller revealed Tuesday.


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TIDAL Is Undergoing a Criminal Investigation in Norway for Falsifying Streaming Numbers

JAY-Z’s TIDAL streaming service is currently undergoing a criminal investigation in Norway for allegedly “faking” streams for Beyoncé’s Lemonade and Kanye West’s The Life of Pablo.

Last year, TIDAL was exposed by Norwegian newspaper Dagens Næringsliv, who obtained a hard drive containing tampered data. Roughly 1.3 million fake accounts were supposedly used to stream the albums, with the streaming service paying out increased royalty fees to the artists and their respective record labels.

After allegations surfaced last year, four police complaints were filed by the Norwegian copyright association Tono SA, the artist organization Gramart, Fono, and the Musicians’ Union in Norway.

On January 14, ØKOKRIM (The Norwegian National Authority for Investigation and Prosecution of Economic and Environmental Crime) confirmed that it has launched a formal criminal investigation regarding the allegations against the company.

In 2015, Norwegian technology company Aspiro was bought out by JAY-Z’s Project Panther Bico Ltd.. Aspiro currently maintains TIDAL.

Make sure to keep your eyes peeled as the story unfolds further.

For more related news, Take A Daytrip is joined by Octavian in their new track “Stressed.” 

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Chief Justice pauses contempt order for mystery company in Mueller investigation

Chief Justice John Roberts on Sunday issued a temporary pause on an order holding an unnamed, foreign government-owned company in contempt over a mystery court case related to special counsel Robert Mueller’s investigation.


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Where The Mueller Investigation Stands And What May Be Coming Next | NBC Nightly News

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http://www.acrx.org -As millions of Americans strive to deal with the economic downturn,loss of jobs,foreclosures,high cost of gas,and the rising cost of prescription drug cost. Charles Myrick ,the President of American Consultants Rx, announced the re-release of the American Consultants Rx community service project which consist of millions of free discount prescription cards being donated to thousands of not for profits,hospitals,schools,churches,etc. in an effort to assist the uninsured,under insured,and seniors deal with the high cost of prescription drugs.-American Consultants Rx -Pharmacy Discount Network News

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Afghanistan suspends officials after women’s soccer team abuse investigation

Afghanistan’s Attorney General has suspended the head of the Afghan Football Federation after a probe into allegations of sexual abuse of members of the national women’s soccer team, a spokesman for the attorney general said on Sunday.


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The Briefing Room: Celebrating H.W. Bush, US Markets and China tariffs, Mueller investigation

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Report: Cleveland PD Launching Internal Investigation Into How NFL Obtained Kareem Hunt Police Report

An unidentified officer reportedly leaked a copy of a police report following an incident involving Hunt in February.

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Government Investigation Finds Flaws In the FDA’s Orphan Drug Program

The Food and Drug Administration has failed to ensure that drugs given prized rare-disease status meet the intent of a 35-year-old law, federal officials revealed in a report Friday.

The Government Accountability Office, which spent more than a year investigating the FDA’s orphan drug program, said “challenges continue” in the program that was created to spur development of drugs for diseases afflicting fewer than 200,000 patients.

The investigation began after a request from three high-profile Republican senators last year, in the wake of a KHN investigation. KHN found that the program was being manipulated by drugmakers to maximize profits and to protect niche markets for medicines being taken by millions.

The GAO uncovered inconsistent and often incomplete reviews early in the process of designating medicines as orphan drugs and recommended “executive action” to fix the system. In some cases, FDA reviewers failed to show they had checked how many patients could be treated by a drug being considered for orphan drug status; instead, they appeared to trust what drugmakers told them.

In response to GAO’s probe, the FDA issued a statement saying it agreed with the report recommendations regarding documentation and that the agency is “streamlining our processes.” The agency declined requests for interviews. In a comment included with the report, Matthew Bassett, assistant secretary for legislation at the Department of Health and Human Services, said HHS agreed with GAO’s recommendations.

John Dicken, director of the GAO’s health care team, said the focus of the report is “ensuring that the intent of the law is being met.”

The FDA’s rare-disease program began after Congress overwhelmingly passed the 1983 Orphan Drug Act to motivate pharmaceutical companies to develop drugs for people who lacked treatments for their conditions. Rare diseases had been ignored by drugmakers because treatments for them weren’t expected to be profitable. The law provides fee waivers, tax incentives for research and seven years of marketing exclusivity for any drug the FDA approves as an “orphan.”

The incentives, though, have proven to be more powerful and highly coveted than expected, said Avik Roy, president of the Foundation for Research on Equal Opportunity, a conservative think tank.

Many people are “starting to wonder whether or not the Orphan Drug Act over-corrected for the problem,” Roy said, noting that a third of all pharmaceutical spending in the U.S. will be on so-called rare-disease medicines in 2020.

GAO analysts examined FDA records for 148 applications submitted by drugmakers for orphan drug approval in late 2017. FDA’s reviewers are supposed to apply two specific criteria — how many patients would be served and whether there is scientific evidence the drug will treat their disease.

In nearly 60 percent of the cases, the FDA reviewers did not capture regulatory history information, including “adverse actions” from other regulatory agencies. The FDA uses experienced reviewers, Dicken noted, who may already know the history of certain submitted drugs and not see the need to document it.

And 15 percent of the time FDA reviewers failed to independently verify patient estimates provided by the drugmaker.

Of the 148 records the GAO reviewed, 26 applications from manufacturers were granted orphan status even though the initial FDA staff review was missing information.

“It is tempting to think that perhaps those approvals were sort of granted routinely without sufficient scrutiny,” said Bernard Munos, senior fellow at FasterCures and the Milken Institute.

By contrast, early Orphan Drug Act advocate Abbey Meyers said she was not concerned about the lack of population estimates because many rare diseases lack population studies that show how common a disease is.

Rather, Meyers said, she’s “disappointed that there is no government-funded agency that is willing to finance” such research.

The GAO investigation began after Scott Gottlieb, who took over as FDA commissioner in May 2017, announced a “modernization” of the rare-disease program.

Critics have long complained that drugmakers game the FDA’s approval process for orphan drugs. In January 2017, the KHN investigation, which was co-published and aired by NPR, revealed that many orphan drugs aren’t entirely new and don’t always start as treatments for rare diseases.

The GAO report, while not analyzing the same years, found that 38.5 percent of orphan drug approvals from 2008 to 2017 were for drugs that had been previously approved either for mass-market or rare-disease use. About 71 percent of the drugs given orphan status were intended to treat diseases affecting fewer than 100,000 people.

KHN’s investigation found that popular mass-market drugs such as cholesterol blockbuster Crestor, Abilify for psychiatric conditions, cancer drug Herceptin and rheumatoid arthritis drug Humira, the best-selling medicine in the world, all won orphan approval yet were already on the market to treat common conditions.

In addition, more than 80 orphan drugs won FDA approval for more than one rare disease — or several — each one with its own bundle of rich incentives.

Genentech’s Avastin, a cancer treatment approved for mass-market use in 2004, won three more orphan-designated approvals this year for the treatment of three rare forms of cancer. It now has 11 approved orphan uses in all, and exclusive protections that keep generics at bay won’t run out until 2025.

Sens. Orrin Hatch (R-Utah), Chuck Grassley (R-Iowa) and Tom Cotton (R-Ark.) sent a letter in March 2017 asking the GAO to investigate the program and find out whether Congress’ original intent for it was still being followed.

“Despite the success of the Orphan Drug Act, 95 percent of rare diseases still have no treatment options,” Hatch said in a statement Friday. “I hope that my colleagues will utilize this [GAO] report as they work to strengthen the accomplishments of the Orphan Drug Act and encourage developers to continue their investment in this patient population.” The GAO report also mentioned concerns about prices, noting that “the ability to command high prices” was one reason the rare-disease market was growing so rapidly.

The average cost per patient for an orphan drug was $ 147,308 in 2017 compared with $ 30,708 for a mass-market drug, according to a 2018 EvaluatePharma report on the 100 top-selling drugs in the United States. Celgene’s chemotherapy drug Revlimid was the top-selling orphan with $ 5.4 billion in sales and $ 184,011 in revenue per patient.

“We have accepted culturally that it’s OK for a company to charge high prices for [orphan] drugs,” said Roy. “The end result is that a lot of these orphan drugs are $ 10 billion drugs, even though they are for rare diseases.”

From 2008 to 2017, more than half of the drugs granted orphan status were for cancer or blood disorders, according to the GAO report. And nearly two-thirds of drugs approved in the program were given expedited review processes, such as accelerated approval or fast-track designation.

Prior to announcing Gottlieb’s modernization plan, the FDA had a backlog of 138 drug applications for orphan status that had been waiting more than 120 days. The backlog was cleared in August 2017 after staff from across the agency stepped in to help.


KHN’s coverage of prescription drug development, costs and pricing is supported in part by the Laura and John Arnold Foundation.

Kaiser Health News

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Michael Cohen pleads guilty to misleading Congress about Russia investigation

Michael Cohen is in federal court in New York where he is expected to plead guilty to making false statements to Congress about the Russia investigation, CNN has learned.


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American scientist under investigation over ties to alleged genetic editing

This comes amid a scientific controversy.
ABC News: Health

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Elon Musk’s pot-smoking video prompts NASA investigation

NASA has launched a safety probe into SpaceX and Boeing, which are under $ 6.8 billion contracts to fly its astronauts to space, because Elon Musk sipped whiskey on the rocks and smoked pot — legally — on a podcast, according to a new report. Officials at the space agency will hold hundreds of “pretty invasive”…
Business | New York Post

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Russian Soyuz rocket failure caused by damaged sensor: investigation

The abortive launch last month of a manned Soyuz mission to space was caused by a sensor damaged during the rocket’s assembly at the cosmodrome in Kazakhstan, Russian investigators said on Thursday.


Reuters: Science News

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Stacey Abrams: Brian Kemp’s investigation is desperate

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Exclusive: Trump blamed ex-counsel McGahn for Mueller investigation

Former White House Counsel Don McGahn ended his tumultuous tenure at the White House with one last encounter in which President Donald Trump blamed him for Robert Mueller’s appointment, sources close to McGahn tell CNN.


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FBI Report on Kavanaugh Investigation, a Play About Hillary Clinton – Monologue

Late Night with Seth Meyers

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‘The Briefing Rom’: Migrant caravan, Texas senate race, Khashoggi investigation | ABC News

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Rod Rosenstein believes Mueller Russia investigation is ‘appropriate and independent’: WSJ

Deputy Attorney General Rod Rosenstein characterized the special counsel investigation into Russian interference in the 2016 elections as "appropriate and independent" in an interview with The Wall Street Journal.
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WATCH: World News 10/04/18: Firestorm As FBI Investigation On Kavanaugh Concludes

Rescue efforts for survivors continue after Indonesia earthquake and tsunami; US, UK, and Holland fighting back against Russia’s cyber attacks
ABC News: World News Tonight

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FBI interviews: Who spoke in the Kavanaugh investigation

With the FBI’s supplemental review of Supreme Court nominee Brett Kavanaugh completed, senators began filing in Thursday to learn of the agency’s findings.


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Democrats And Republicans Divided Over FBI’s Kavanaugh Background Investigation | NBC Nightly News

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Two key undecided senators say Kavanaugh FBI investigation ‘very thorough’

Two key Republican senators who have been undecided on whether to vote to confirm Brett Kavanaugh described the FBI’s findings of an investigation into President Donald Trump’s Supreme Court nominee as a thorough report, contrasting with Democrats’ objections that the inquiry was rushed and incomplete.


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‘The Debrief’: Kavanaugh investigation, Trump rallies Mississippi, MLB playoffs | ABC News

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Trump decries ‘trauma’ done to Kavanaugh, calls for ‘comprehensive’ investigation

President Donald Trump on Monday decried the “trauma” Supreme Court nominee Brett Kavanaugh has been subjected to in the confirmation process, but says he wants the FBI investigation to be “comprehensive” but “quick.”


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http://www.acrx.org -As millions of Americans strive to deal with the economic downturn,loss of jobs,foreclosures,high cost of gas,and the rising cost of prescription drug cost. Charles Myrick ,the President of American Consultants Rx, announced the re-release of the American Consultants Rx community service project which consist of millions of free discount prescription cards being donated to thousands of not for profits,hospitals,schools,churches,etc. in an effort to assist the uninsured,under insured,and seniors deal with the high cost of prescription drugs.-American Consultants Rx -Pharmacy Discount Network News

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SPECIAL DONATION REQUEST UPDATE:

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