Elucidation of functional mechanism of ‘love hormone,’ oxytocin, at molecular level

Oxytocin is essential in activities of the social brain such as trust and love and in maternal bonding behaviors. It is produced in the brain and secreted into the circulation. Here, by analyzing maternal behaviors of RAGE gene-manipulated mice, oxytocin was found to be transported back to the brain, crossing the blood-brain barrier (BBB), an extremely effective barrier, by binding to the receptor for advanced glycation end-products (RAGE) on capillary endothelial cells of the BBB.
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Measles accelerates to second-highest level in US in 25 years and over 100,000 global cases

The number of measles cases in the United States made its biggest jump of the year, with 90 new cases reported in just one week, according to numbers released Monday by the US Centers for Disease Control and Prevention.


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Infant sleep duration associated with mother’s level of education and prenatal depression

A new study analyzing data from Canadian parents has found that babies sleep less at three months of age if their mothers do not have a university degree, experienced depression during pregnancy or had an emergency cesarean-section delivery.
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Sophie Turner and Joe Jonas are taking their relationship to the next level

It’s happening!!!

Sophie Turner is one of the most talked-about women in the world, shaping up to be one of Game of Thrones’ most exciting success stories.

Whether she’s showing off her acting chops as GoT’s Sansa Stark or taking down Piers Morgan for his controversial views on mental health, the 22-year-old never fails to make viral news.

A lot of the speculation around her however centres on her relationship with fiancé Joe Jonas, with the couple announcing their engagement in 2017.

Ever since the news, the LA power couple has been ticking off relationship milestones left, right and centre.

From being each other’s wedding dates and becoming Instagram official to bonding with their future brothers and sisters in law, they’ve almost done it all. But it was this week, that the betrothed couple ramped it up a gear.

sophie turner following

Joe and Sophie were spotted house hunting in Los Angeles, adding fuel to the rumours that they were moving in together, something that would make sense, ahead of the couple’s wedding – set for this summer.

The ceremony is rumoured to be taking place in France, and there’s sure to be a lot of A-listers in attendance. We’re expecting at least a few former Disney stars and of course the extended Game of Thrones cast.

Congratulations to Sophie and Joe!

The post Sophie Turner and Joe Jonas are taking their relationship to the next level appeared first on Marie Claire.

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Turkey Capacity Utilization Steady At Lowest Level Since 2015

Turkey’s manufacturing capacity utilization rate was unchanged in December at its lowest level since early 2015, figures from the Turkish central bank showed on Wednesday.
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Dolce, Gabbana Cleared of Tax Evasion at Fiscal Level

TAX BREAK: Despite their recent scandal in China, Domenico Dolce and Stefano Gabbana have reason to celebrate the holidays: The designers have been cleared of tax evasion charges also at a fiscal level.
While Dolce and Gabbana were acquitted in 2014 at a penal level at the end of seven years of legal troubles — which included an acquittal from charges of fraud from a judge at the preliminary hearing level in 2011, a reversal at a higher court, new charges of tax evasion and two trials at lower court — fiscally in Italy the issue was not resolved and meant they could be hit by a fine by the tax commission. Case in point, in March 2013, Italy’s tax commission fined the designers 343.4 million euros, plus interest.
The fine by the tax commission is separate from the tax evasion trials, but both stem from the same accusations put forward by Italy’s Internal Revenue Agency of omitted and unfaithful earnings declarations.
The designers were charged with alleged tax evasion totaling 416 million euros related to the 2004 sale of the Dolce & Gabbana and D&G brands to the designers’ Luxembourg-based holding company, Gado Srl. The Italian tax police reportedly considered Gado essentially a

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Gun deaths in US reach highest level in nearly 40 years, CDC data reveals

Nearly 40,000 people in the United States died by guns last year, marking the highest number of gun deaths in 38 years, according to a new analysis of data from the Centers for Disease Control and Prevention’s WONDER database.


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Kerry Washington’s Designer Boot Collection Is Next Level and Very Expensive

ESC: Kerry WashingtonIf most boots are made for walking, Kerry Washington’s boots are made for strutting.
No one wear boots like the Scandal star. From street style to the red carpet, we’ve taken…

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Stocks just broke a key level and what’s next could decide fate of bull market

The stock market sell off sent the S&P 500 below a key level Tuesday morning, and how it trades next could determine whether the market is close to finding a bottom or more selling is ahead.
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