Exposure to organochlorine pesticides in the womb linked to poorer lung function in childhood

Babies exposed to higher levels of organochlorine compounds in the womb go on to have worse lung function in childhood, according to new research. These compounds, which include the pesticide DDT, as well as electrical insulators and other industrial products, are now banned in most parts of the world. However, because they degrade very slowly, they are still present in the environment and in foods.
Child Development News — ScienceDaily

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Childhood trauma linked to impaired social cognition later in life for patients with major psychiatric disorders

A new report has identified a significant association between childhood adversity and impaired social cognitive functioning among adults diagnosed with major psychiatric disorders.
Child Development News — ScienceDaily

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Parental cancer linked to poorer school grades, educational attainment, and adult earning power

Childhood experience of parental cancer is linked to poorer school grades, educational attainment, and subsequent earning power as a young adult, suggests a data linkage study of more than one million Danes.
Child Development News — ScienceDaily

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Aggressive form of breast cancer linked to gene

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http://www.acrx.org -As millions of Americans strive to deal with the economic downturn,loss of jobs,foreclosures,high cost of gas,and the rising cost of prescription drug cost. Charles Myrick ,the President of American Consultants Rx, announced the re-release of the American Consultants Rx community service project which consist of millions of free discount prescription cards being donated to thousands of not for profits,hospitals,schools,churches,etc. in an effort to assist the uninsured,under insured,and seniors deal with the high cost of prescription drugs.-American Consultants Rx -Pharmacy Discount Network News

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Food for thought: How the brain reacts to food may be linked to overeating

The reason why some people find it so hard to resist finishing an entire bag of chips or bowl of candy may lie with how their brain responds to food rewards, according to researchers who found that when certain regions of the brain reacted more strongly to being rewarded with food than being rewarded with money, those people were more likely to overeat.
Consumer Behavior News — ScienceDaily

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Digital media use linked to behavioral problems in kids

Teens who spend lots of time using digital devices are prone to psychiatric problems, reports a team of scientists in a new study. Children who are heavy users of digital devices are twice as likely as infrequent users to show symptoms of attention-deficit/hyperactivity disorder (ADHD), the study finds.
Teen Health News — ScienceDaily

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Treasury probe of bank linked to Kushner loans is ‘ongoing’

The US Treasury Department is continuing to investigate a California bank that has lent money to and bought mortgages from presidential son-in-law Jared Kushner’s real estate company, The Post has learned. BOFI Holding, previously known as Bank of Internet USA, is under investigation by the department’s Office of Inspector General, the agency’s counsel, Rich Delmar,…
Business | New York Post

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Obesity Linked To Smoking

Obesity Linked To Smoking

Being obese is associated with an increased risk of taking up smoking and smoking frequency (number of cigarettes smoked per day), finds a study published by The BMJ today.

These results strongly suggest that obesity influences smoking behavior, which could have implications for public health interventions aiming to reduce the prevalence of these important risk factors, say the researchers.

It is…

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Sleep Loss Linked To Obesity And Diabetes

Nighttime snacking and junk food cravings may contribute to unhealthy eating behaviors and represent a potential link between poor sleep and obesity, according to a study by University of Arizona Health Sciences sleep researchers. The study was conducted via a nationwide, phone-based survey of 3,105 adults from 23 U.S. metropolitan …

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Sleep Loss Linked To Obesity And Diabetes

Sleep Loss Linked To Obesity And Diabetes

Nighttime snacking and junk food cravings may contribute to unhealthy eating behaviors and represent a potential link between poor sleep and obesity, according to a study by University of Arizona Health Sciences sleep researchers.

The study was conducted via a nationwide, phone-based survey of 3,105 adults from 23 U.S. metropolitan areas. Participants were asked if they regularly consumed a…

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Autism is not linked to eating fish in pregnacy

A major study examining the fish-eating habits of pregnant women has found that they are not linked to autism or autistic traits in their children. Scientists looked at the assumption that mercury exposure during pregnancy is a major cause of autism using evidence from nearly 4,500 women who took part in the Children of the ’90s study.
Child Development News — ScienceDaily

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Discovery Of New Protein Linked To Breast Cancer

Discovery Of New Protein Linked To Breast Cancer

Researchers experimentally block the spread of a type of breast cancer.

Jean-François Côté, a researcher at the Montreal Clinical Research Institute (IRCM) and professor at Université de Montréal’s Faculty of Medicine, studies metastasis, the leading cause of cancer-related death. Recently, his team uncovered a protein that, once deactivated, could prevent the development of metastases in an…

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Viewing more medical marijuana ads linked to higher pot use among adolescents

As prohibitions on the sale and use of marijuana ease, one result is more advertising about cannabis. A new study suggests that may have consequences on adolescents, with those who view more advertising for medical marijuana being more likely to use marijuana, express intentions to use the drug and have more-positive expectations about the substance.
Consumer Behavior News — ScienceDaily

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How a Russian oligarch linked to Trump lawyer Michael Cohen turned a California state park into a mini Moscow

Viktor Vekselberg has been banned from doing business in America under U.S. sanctions. But as of this week, he was still the chairman of a U.S. nonprofit group.
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Greater Burden of Atrial Fibrillation Linked to Higher Stroke Risk

OAKLAND, Calif. — Among people with intermittently recurring atrial fibrillation who are not taking anti-blood-clotting medications, those whose hearts were in abnormal rhythms longer were three times more likely to have strokes or other types of blood clots than those who had abnormal heart rhythms for less time, according to a new Kaiser Permanente study.

Continuous heart monitoring may help physicians identify patients at higher risk and tailor treatments, according to the study published today in JAMA Cardiology.

Alan S. Go, MD

Alan S. Go, MD

“In our study, in people with the greatest burden of intermittently recurring atrial fibrillation  those with the greatest burden defined as more than 11 percent of the time — were the most likely to experience subsequent strokes or arterial blood clots, even after we controlled for all other important risk factors,” said lead author Alan S. Go, MD, director of the Comprehensive Clinical Research Unit within the Kaiser Permanente Division of Research.

Both types of atrial fibrillation — intermittently recurring and that which occurs 100 percent of the time — can produce irregular and fast heartbeats, or arrhythmias. They affect millions of adults in the United States, and are linked to a higher risk of ischemic strokes and other types of blood clots. Currently, patients with any amount of atrial fibrillation are treated the same as those with chronic atrial fibrillation when it comes to stroke prevention, but whether these groups have an equal risk of strokes and blood clots has been controversial, explained Dr. Go.

The Kaiser Permanente Real-World Heart Monitoring Strategy Evaluation, Treatment Patterns, and Health Metrics in Atrial Fibrillation (known as KP-RHYTHM) study used a non-invasive, continuous electrocardiographic device to gather data on the amount of time people spent in the arrhythmias. Approved by the Food and Drug Administration, the monitoring device is a lightweight patch that adheres to the upper left chest, recording and storing beat-to-beat information for up to two weeks.

The study analyzed heart rhythm data for 1,965 adult members of Kaiser Permanente living in California with confirmed intermittently recurring atrial fibrillation and is among the largest to employ continuous, non-invasive heart monitoring. Participants wore the monitoring device continuously for up to 14 days between October 2011 and October 2016 and were not taking anti-blood clotting medications during that time.

Study participants were followed through November 2016 to identify those hospitalized for ischemic stroke or arterial blood clots (thromboembolism) while not taking anti-blood-clotting (anti-coagulation) medications such as warfarin or direct oral anticoagulants.

Matthew Solomon, MD

Matthew Solomon, MD

“This study has the potential to have a major impact on heart care,” said senior author Matthew D. Solomon, MD, PhD, a cardiologist at Kaiser Permanente in Oakland, California, and adjunct researcher at the Division of Research. “Using new continuous heart-monitoring technology, physicians can identify patients with intermittently recurring atrial fibrillation at greater risk and engage in better-informed shared decision-making around stroke prevention strategies.”

This study was supported by a research grant from iRhythm Technologies, Inc.

In addition to Drs. Go and Solomon, co-authors were: Kristi Reynolds, PhD, MPH, and Teresa N. Harrison, SM, Department of Research and Evaluation, Kaiser Permanente Southern California; Jingrong Yang, MA, and Sue Hee Sung, MPH, Division of Research, Kaiser Permanente Northern California; Nigel Gupta, MD, Kaiser Permanente Los Angeles Medical Center; Judy Lenane, RN, MHA, iRhythm Technologies; and Taylor I. Liu, MD, PhD, Kaiser Permanente Santa Clara Medical Center.


About the Kaiser Permanente Division of Research
The Kaiser Permanente Division of Research conducts, publishes and disseminates epidemiologic and health services research to improve the health and medical care of Kaiser Permanente members and society at large. It seeks to understand the determinants of illness and well-being, and to improve the quality and cost-effectiveness of health care. Currently, DOR’s 550-plus staff is working on more than 350 epidemiological and health services research projects. For more information, visit divisionofresearch.kaiserpermanente.org or follow us @KPDOR.

About Kaiser Permanente
Kaiser Permanente is committed to helping shape the future of health care. We are recognized as one of America’s leading health care providers and not-for-profit health plans. Founded in 1945, Kaiser Permanente has a mission is to provide high-quality, affordable health care services and to improve the health of our members and the communities we serve. We currently serve more than 12 million members in eight states and the District of Columbia. Care for members and patients is focused on their total health and guided by their personal Permanente Medical Group physicians, specialists and team of caregivers. Our expert and caring medical teams are empowered and supported by industry-leading technology advances and tools for health promotion, disease prevention, state-of-the-art care delivery and world-class chronic disease management. Kaiser Permanente is dedicated to care innovations, clinical research, health education and the support of community health. For more information, go to share.kaiserpermanente.org.

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The Russian MMA Fighter Linked to Trump, Cohen—and Putin

Photo Illustration by The Daily Beast

The Russian fighter was in Chicago, killing time with his entourage in the days before a mixed martial arts bout, when the call came.

FBI agents were looking for him. A fearsome heavyweight known as “The Last Emperor”—and who’s beloved by Russian President Vladimir Putin—Fedor Emelianenko had been in America for only five days before the feds appeared at his hotel near O’Hare Airport on Tuesday, April 24.

A decade before, Emelianenko had headlined an MMA league championed by Donald Trump and his personal lawyer and fixer, Michael Cohen. The outfit went bust after only two fights.

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http://www.acrx.org -As millions of Americans strive to deal with the economic downturn,loss of jobs,foreclosures,high cost of gas,and the rising cost of prescription drug cost. Charles Myrick ,the President of American Consultants Rx, announced the re-release of the American Consultants Rx community service project which consist of millions of free discount prescription cards being donated to thousands of not for profits,hospitals,schools,churches,etc. in an effort to assist the uninsured,under insured,and seniors deal with the high cost of prescription drugs.-American Consultants Rx -Pharmacy Discount Network News

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Playing Youth Tackle Football Is Linked to Earlier Symptoms of Brain Disease

Playing football professionally has been linked to chronic traumatic encephalopathy (CTE), a degenerative brain disease. But what happens to children who start the sport early, before they even turn 12?

That’s the question neuropathologist Dr. Ann McKee, whose groundbreaking work on CTE has uncovered the neurological risks of playing football, set out to answer in a new study published in the Annals of Neurology. In her team’s analysis of the brains of 211 deceased football players who had been diagnosed with CTE, along with detailed behavioral questionnaires filled out by their relatives and interviews with family members, McKee expected to find more severe signs of the condition in people who started the game young. These would be visible in more pronounced deposits of tau protein, which kills brain cells, in the brains of men who sustained hundreds — if not thousands — of extra head impacts as children.

To McKee’s great surprise, however, early exposure to tackle football was not associated with more severe signs of CTE, or other brain diseases like Alzheimer’s. Instead, she found something perhaps even more disturbing. Football players who played tackle football as children suffered the devastating symptoms of brain disease, like cognitive impairment and mood swings, earlier in their lives.

By analyzing the 211 brains, McKee and her team found that those who played tackle football before age 12 — 84 players in total — had an earlier onset of cognitive, behavior and mood symptoms by an average of 13 years, compared to those who started after age 12. Every one year younger the participants began playing tackle football predicted earlier onset of cognitive, behavioral and mood problems by about 2.5 years. Of these 211 men with CTE, 76 were amateur players, and 135 played at the professional level.

“It’s as though the brain of these people who started playing early football was less resilient to pathology,” says McKee, chief of neuropathology at Boston VA Healthcare System, and director of Boston University’s CTE Center. “It’s sort of like they have a weakened nervous system, and set you up for earlier onset of any of these disorders. That was a surprising finding.”

Evidence suggests that even if you don’t end with up CTE — a disease closely linked to football that can only be diagnosed after a brain autopsy — strapping on a helmet as a kid can be risky. Among the 35 players without CTE in the study, those who played football before age 12 had an earlier onset of cognitive symptoms by an average of 20 years, and behavior and mood symptoms by 22 years. (Because of this small sample size of players without CTE, however, this finding is not statistically significant). Of those 35 players, 26 had other neuropathological diagnoses such as Alzheimers, Lewy body pathology, frontotemporal lobar degeneration and axonal injury.

This study has limitations. The brains used in this study may not represent those of the broader tackle football population, because most ex-football players, and their families, chose to donate their brains to shed light on their cognitive and behavioral struggles. Still, the results are alarming. “The data supports that you should not play tackle football until you’re more physically mature,” says McKee, whose future work will attempt to define a sort of tipping point for tackle football: how long can kids play before the risks rise exponentially?

Last week, California lawmakers dropped legislation banning tackle football for children under 12, and a similar measure has stalled in Illinois. But the momentum for limiting hits is expected to keep growing. “The cost-benefit of playing eight years before high school is so far on the side of being foolish, it’s inevitable that this change takes place,” says former San Francisco 49ers linebacker Chris Borland, who retired in 2015 at age 24 because he was concerned about the long-term effects of repetitive head trauma. Borland started playing football in the ninth grade. “The research is going to continue to come out. It gets harder to justify young kids playing.”

Football can still thrive if the youngest kids stopped playing tackle. Tom Brady, for example, did not play Pop Warner, the largest youth football program in the U.S. Michigan coach Jim Harbaugh — who loves football more than anyone — has said that kids should play soccer until eighth grade, to learn footwork and agility, before strapping on shoulder pads in high school.

The stakes in this debate are high. “We all want our kids to grow up to be the most productive, most successful of society they can possibly be,” says McKee. “And this is something that may limit their ultimate potential to be highly successful and highly productive in later life.”

Sports – TIME

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Maternal binge drinking linked to mood problems and alcohol abuse in offspring

A new study is the first to show that binge drinking by expectant mothers can impair the mental health of their offspring. Researchers report that rat mothers who drank in a binge-like manner during pregnancy and lactation were more prone to depressive behaviors — and so were their offspring. Moreover, alcohol-triggered heritable changes in the mother made their offspring more vulnerable to mood disturbances and alcohol abuse as adolescents.
Teen Health News — ScienceDaily

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For racial minority adolescents, cigarette and alcohol use linked to suicidality

Examining more than 20 years of national data for US adolescents, a research team reports that adolescents have high prevalence of alcohol, cigarette, and marijuana use, and concerning rates of suicide-related thoughts and behaviors. The data show that among U.S. adolescents in ninth to 12th grades, 75 percent had used alcohol, 58 percent had used cigarettes, and 41 percent tried marijuana.
Teen Health News — ScienceDaily

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35 reported cases of E. coli linked to romaine lettuce: CDC

CDC recommends that romaine lettuce from Yuma, Arizona be thrown out.
ABC News: Health

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Inflammation during pregnancy is linked to baby’s brain

A study has established a link between inflammation in pregnant women and the way the newborn brain is organized into networks. The results may provide promising avenues to explore treatments with potential to change these negative impacts on newborn brain function.
Child Development News — ScienceDaily

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Adults’ political leanings linked with early personality traits

Our political attitudes in adulthood have roots in early childhood temperament, according to new findings. Analyses of data from more than 16,000 participants in two longitudinal studies in the United Kingdom reveal links between conduct problems at ages 5 and 7 and economic and political discontent 25 years later.
Child Development News — ScienceDaily

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Early growth after pre­term birth is linked to cog­nit­ive func­tion­ing in adult­hood

Preterm born children are more likely to have problems in cognitive functioning and mental health. Then again, most preterm infants grow up to be just as happy, healthy and smart as their peers. Among the preterm infants, who are at risk?
Child Development News — ScienceDaily

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Brain development disorders in children linked to common environmental toxin exposures

Exposures of pregnant women and children to common thyroid-hormone-disrupting toxins may be linked to the increased incidence of brain development disorders, according to new research. The review describes how numerous, common chemicals can interfere with normal thyroid hormone actions, which are essential for normal brain development in fetuses and young children, and suggests a need for greater public health intervention.
Child Development News — ScienceDaily

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Early numeracy performance of young kids linked to specific math activities at home

New research finds links between certain math skills in young children and specific numerical activities undertaken at home with parents. The study also finds that the more parents engage in mathematical activities with their children, the higher their early numeracy performance.
Infant and Preschool Learning News — ScienceDaily

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Teen childbirth linked to increased risk for heart disease

Women who become teen-age mothers may be significantly more likely to have greater risks for cardiovascular disease later in life than older mothers. Unlike previous studies, among women who had children the overall number of births was unrelated to greater cardiovascular risk.
Teen Health News — ScienceDaily

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Insomnia linked to alcohol-use among adolescents, study shows

‘Parents, educators, and therapists should consider insomnia to be a risk marker for alcohol use, and alcohol use a risk marker for insomnia, among early adolescents,’ writes Rutgers-Camden researcher Naomi Marmorstein in the study, published recently in the journal Addictive Behaviors.
Teen Health News — ScienceDaily

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Childhood aggression linked to deficits in executive function

Researchers find that primary school children with reduced cognitive skills for planning and self-restraint are more likely to show increased aggression in middle childhood. The study examined the relationship between aggression and executive function — a measure of cognitive skills that allow a person to achieve goals by controlling their behavior. The results suggest that helping children to increase their executive function could reduce their aggression.
Child Development News — ScienceDaily

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Two behaviors linked to high school dropout rates

The factors that may lead to a student’s decision to leave school are complex, but a new study sheds light on how two behaviors — aggression and weak study skills — contribute to the problem.
K-12 Education News — ScienceDaily

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Cramer Remix: Surprise! Defense stocks’ struggles aren’t linked to tariffs

Jim Cramer gives a fresh perspective on what could be causing defense stocks to fall recently.
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Air pollution linked to brain alterations and cognitive impairment in children

A new study performed in the Netherlands has linked exposure to residential air pollution during fetal life with brain abnormalities that may contribute to impaired cognitive function in school-age children. The study reports that the air pollution levels related to brain alterations were below those considered to be safe.
Child Development News — ScienceDaily

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Exposure to childhood violence linked to psychiatric disorders

Investing in diminishing socioeconomic status inequalities and in preventing violent events during childhood may improve the mental health of youths from low socioeconomic status backgrounds. The results showed that having experienced any traumatic event and low socioeconomic status were associated with an internalizing disorder such as depression and anxiety and an externalizing disorder including attention-deficit hyperactivity.
Parenting News — ScienceDaily

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Increased air pollution linked to bad teenage behavior

A new study linking higher levels of air pollution to increased teenage delinquency is a reminder of the importance of clean air and the need for more foliage in urban spaces. The study suggests ambient air pollution may increase delinquent behavior among 9- to 18-year-olds in urban neighborhoods in Greater Los Angeles. The insidious effects are compounded by poor parent-child relationships and parental mental and social distress, researchers report.
Teen Health News — ScienceDaily

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Abuse and adversity in childhood linked to more cardiovascular risk in adulthood

Children and teens who experience abuse, bullying, neglect or witness violence and other forms of adversity are more likely to develop heart and blood vessel diseases as adults. Unhealthy responses to stress (such as overeating), mental health problems and disruptions in basic biologic processes may underlie the increased risk.
Teen Health News — ScienceDaily

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Air pollution linked to irregular menstrual cycles

The air your teenage daughter breathes may be causing irregular menstrual cycles. Well documented negative health effects from air pollution exposure include infertility, metabolic syndrome and polycystic ovary syndrome. This study is the first to show that exposure to air pollution among teen girls (ages 14-18) is associated with slightly increased chances of menstrual irregularity and longer time to achieve such regularity in high school and early adulthood.
Teen Health News — ScienceDaily

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Ibuprofen linked to male infertility: study

Men who regularly take ibuprofen may be putting their fertility at risk, a study claims. Experts found the painkillers reduce levels of key male sex hormones needed for healthy sperm. They fear long-term use may be to blame for rising levels of infertility. It follows previous research, which shows baby boys born to women who…
Living | New York Post

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Pennsylvania Dem linked to gambling ring awaits sentencing

Former Pennsylvania state Rep. Marc Gergely – who resigned last month – is awaiting sentencing next week on corruption charges in relation to an illegal gambling machine ring.
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A New Study Says Use of Birth Control Is Linked To Increased Chances Of Breast Cancer

According to a study done in Denmark, women who have used hormonal contraception are at an increased risk for being diagnosed with breast cancer.

The study followed over a million women for 10 years who used contraceptives such as the …


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Kushner likely linked to Flynn’s court docs

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Three coffees a day linked to range of health benefits, study says

People who drink three or four cups of coffee every day could significantly reduce the chances of early death, a new study suggests.
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Too Hot to Sleep? Severe Hot Flashes Linked to Greater Risk of Obstructive Sleep Apnea

Early diagnosis important to control risk of heart disease, stroke, depression, and death

Source: The North American Menopause Society (NAMS)

Many menopausal women complain about poor sleep. Should the problem be blamed simply on menopause or on a more serious underlying sleep disorder such as obstructive sleep apnea (OSA)? What, if any, is the connection between hot flashes, which can also lead to cardiovascular risk, and OSA? New study results being published online today in Menopause, the journal of The North American Menopause Society (NAMS), examine that relationship.

“Early morning headaches or excessive daytime sleepiness should raise concern for OSA and signal a possible need for sleep apnea testing.” – Dr. JoAnn Pinkerton, NAMS executive director

Up to 80% of midlife women experience hot flashes or night sweats. Although there is a known association between hot flashes and sleep disturbances in midlife women, it has proven difficult to distinguish those sleep disturbances directly related to menopause from those because of OSA and other sleep disorders. Obstructive sleep apnea, which is more common in men than women, occurs more frequently as women age, gain weight, and reach perimenopause and postmenopause status. A sampling of perimenopausal and postmenopausal women who experienced disturbed sleep showed that 53% had a sleep disorder such as OSA, restless leg syndrome, or both.

The diagnosis of OSA in women can be more challenging because their symptoms are different from the more obvious ones that men experience, such as loud snoring. Symptoms for women more often include insomnia, headaches, fatigue, depression, and anxiety. Despite the challenges, the identification of OSA is important because it is associated with a significantly increased risk of heart disease, hypertension, stroke, depression, and death.

As reported in “Association of vasomotor symptoms and sleep apnea risk in midlife women,” 1,691 women from the Mayo Clinic completed questionnaires. Of these women, 24.9% were classified in the intermediate and high-risk categories for OSA. These women were likely to be older and have a higher body mass index and a greater incidence of hypertension, among other findings. More pertinent to the results of this study was the fact that women reporting severe hot flashes in midlife were at a higher risk for OSA — 1.87 times higher than in women with mild or no hot flashes.

“Sleep disruption is a common complaint at menopause. It is important to recognize the high number of undiagnosed sleep disorders, including OSA,” says Dr. JoAnn Pinkerton, NAMS executive director. “Early morning headaches or excessive daytime sleepiness should raise concern for OSA and signal a possible need for sleep apnea testing.”

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Too Hot to Sleep? Severe Hot Flashes Linked to Greater Risk of Obstructive Sleep Apnea

Too Hot to Sleep? Severe Hot Flashes Linked to Greater Risk of Obstructive Sleep Apnea

Early diagnosis important to control risk of heart disease, stroke, depression, and death Source: The North American Menopause Society (NAMS) Many menopausal women complain about poor sleep. Should the problem be blamed simply on menopause or on a more serious underlying sleep disorder such as obstructive sleep apnea (OSA)? What, if any, is the connection between hot flashes, which can also lead…

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Madagascar plague linked to ritual dance with dead bodies

The deadly plague sweeping Madagascar may have a particularly gruesome cause — a local tradition of dancing with dead bodies. Health officials suspect it’s no coincidence that the outbreak — which has infected more than 1,100 people and killed 124 since August — coincides with the time of year when families customarily exhume the remains…
News | New York Post

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Statins Linked to Lower Rates of Breast Cancer and Mortality

Statins Linked to Lower Rates of Breast Cancer and Mortality

A 14 year study in more than one million people has found that women with high cholesterol have significantly lower rates of breast cancer and improved mortality. The research, presented at European Society of Cardiology Congress, suggests that statins are associated with lower rates of breast cancer and subsequent mortality. “This is the most conclusive and direct evidence as yet to confirm the…

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Statins Linked to Lower Rates of Breast Cancer and Mortality

A 14 year study in more than one million people has found that women with high cholesterol have significantly lower rates of breast cancer and improved mortality. The research, presented at European Society of Cardiology Congress, suggests that statins are associated with lower rates of breast cancer and subsequent mortality.

“This is the most conclusive and direct evidence as yet to confirm the link between high cholesterol and breast cancer, a topic that has been fascinating researchers for the past few years,” said Dr Rahul Potluri, senior author and founder of the ACALM Study Unit at Aston Medical School, Aston University, Birmingham, UK.

“Showing that patients with high cholesterol have a lower risk of developing breast cancer and subsequent mortality in a longitudinal study like this provides the strongest evidence for a protective effect, which is likely related to statins. -Dr Rahul Potluri”

“We previously found an association between having high cholesterol and developing breast cancer so we designed this study to follow up patients longitudinally and address the relationship more robustly,” he continued. “Showing that patients with high cholesterol have a lower risk of developing breast cancer and subsequent mortality in a longitudinal study like this provides the strongest evidence for a protective effect, which is likely related to statins.”

The current study followed-up women aged 40 or more with, and without, a diagnosis of high cholesterol and compared the development of breast cancer and subsequent mortality rates in the two groups. Patients admitted to UK hospitals with high cholesterol between 1 January 2000 and 31 March 2013 were recruited from the Algorithm for Comorbidities, Associations, Length of stay and Mortality (ACALM) clinical database. They were followed-up until 2013 for a new diagnosis of breast cancer and subsequent mortality obtained from the Office for National Statistics. Analyses were performed to adjust for demographic and clinical characteristics between the groups.

Out of a total of 1 220,024 patients in the ACALM study, there were 16,043 women with high cholesterol aged 40 or over who were compared to an equivalently sized and age-matched group of patients without high cholesterol.

The researchers found that those with high cholesterol were 45% less likely to develop breast cancer than those without high cholesterol. After adjusting for factors which might influence mortality, including age, sex, ethnicity, and the ten most common causes of death in the UK, the researchers found that patients who developed breast cancer were 40% less likely to die if they had high cholesterol than if they did not.

Dr Potluri said: “Compared to those without high cholesterol, patients with high cholesterol had a 45% reduced risk of breast cancer, and if they did develop breast cancer, a 40% reduced chance of death. If a diagnosis of high cholesterol leads to lower breast cancer rates this must either relate to something inherent in the condition or affected patients, or more likely, to treatment with widely used cholesterol lowering interventions such as statins.”

Dr Paul Carter, lead author of this study and researcher at the ACALM Study Unit, said: “Our research confirms that women with a diagnosis of high cholesterol have strikingly lower rates of breast cancer with improved death rates and survival. Building on previous research by us and other groups, including animal studies in which statins reduced the risk of breast cancer, this gives a strong indication that statins produce this protective effect in breast cancer.”

“Statins have some of the best mortality evidence amongst all cardiovascular medications and their use in patients with a diagnosis of high cholesterol is likely the reason this diagnosis appears to be protective against the development of breast cancer and subsequent mortality,” continued Dr Carter.

He added: “The results of this study provide the strongest justification to date for a clinical trial evaluating the protective effect of statins in patients with breast cancer, and this is what we intend to do.”

Dr Carter concluded: “Patients with breast cancer who have high cholesterol, people at high risk of cardiovascular disease, and those with established cardiovascular disease should be given statins according to current guidelines. I don’t think at the moment we can give statins to prevent or reduce mortality from breast cancer per se. But a positive result in a clinical trial could change this and it is an exciting and rapidly progressing field.”

 

Materials provided by European Society of Cardiology.

The post Statins Linked to Lower Rates of Breast Cancer and Mortality appeared first on Women's Health.

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Were Downed Power Lines Linked to California Wine Country Fires?

When the first reports of multiple fires in California’s Sonoma County poured in Sunday night, emergency dispatchers were at the same time sending out fire crews to investigate downed PG&E power lines and exploding electrical transformers in the area, the East Bay Times reports. Personnel were reportedly sent out to at least 10 locations over a 90-minute period to look into sparking wires and other electrical-system problems. San Francisco-based utility PG&E and others in the state have been in the past found responsible for major destructive wildfires over power-line maintenance issues. The utility released a statement Tuesday night acknowledging the equipment issues over the weekend in Sonoma—reportedly caused by high “hurricane-strength” winds—but noted that any broader questions about maintenance issues causing the area’s wildfires are at this point “highly speculative.” In April, PG&E was fined $ 8.3 million for a power-line maintenance problem that caused the September 2015 Butte Fire in Amador County. State fire officials are still investigating the cause of the Wine Country blazes, which are only 40 percent contained. As of late Tuesday night, the wildfires ravaging the area had killed at least 17 people and destroyed more than 2,000 homes in multiple counties.

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Officials: White nationalist rally linked to 3 deaths

CHARLOTTESVILLE, Va. (AP) — A car plowed into a crowd of people peacefully protesting a white nationalist rally Saturday in a Virginia college town, killing one person, hurting at least two dozen more and ratcheting up tension in an increasingly violent confrontation.
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Officials: White nationalist rally linked to 3 deaths

CHARLOTTESVILLE, Va. (AP) — A car plowed into a crowd of people peacefully protesting a white nationalist rally Saturday in a Virginia college town, killing one person, hurting at least two dozen more and ratcheting up tension in an increasingly violent confrontation.
Top Headlines

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Chinese firm’s trader linked to unmasking of Bloomberg chat users

Moataz Abed, the trader who seems to have been in contact with an e-mail address that blasted out a list of anonymous Bloomberg chat participants, works at Noble Group, a China-based energy trading company that has tried to root out names of unidentified analysts, The Post has learned. In 2015, publicly traded Noble sued rival…
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