MLB roundup: Indians’ Kluber breaks arm in loss

Light-hitting Rosell Herrera went 2-for-4 with three RBIs on Wednesday, leading the host Miami Marlins to a 4-2 win over the Cleveland Indians, who lost right-hander Corey Kluber to a non-displaced fracture in his pitching forearm.


Reuters: Sports News

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Mike Novogratz’s Crypto Bank Galaxy Digital Posts $272.7 Mln Loss In FY18

Billionaire Michael Novogratz’s crypto investment bank Galaxy Digital Holding Ltd. reported a loss of $ 272.64 million in fiscal 2018 reflecting significant loss on digital assets amid the weakness in cryptocurrency market. Novogratz said, “The first few months of 2019 have yielded a notable increase in activity across our business lines….”
RTT – Top Story

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Musk suggests capital infusion after projected $700M loss

Tesla Chief Executive Elon Musk suggested on Wednesday a capital raise could be imminent, as the electric-vehicle maker posted a first-quarter loss of $ 700 million and predicted a return to profit in the third. Tesla plans to resolve logistics issues with global vehicle deliveries after weathering a challenging few months, also marked by staff layoffs…
Business | New York Post

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Sarah Hyland Talks Hair Loss, Regrowth, and Her Newfound Curls: Interview

Olay teamed up with Sarah Hyland and five other influencers to celebrate its #SkinTransformed campaign in its first-ever waterproof photography bath book, which highlights their transformation stories and encourages people to slow down and enjoy bathtime. Allure talked to Hyland ahead of the campaign reveal to learn more about her journey — here’s what she had to say.
Allure

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Dow, S&P 500 Close Higher But Nasdaq Posts Modest Loss – U.S. Commentary

Stocks turned in a relatively lackluster performance during trading on Thursday, with the major averages ending the day on opposite sides of the unchanged line. Despite the choppy trading, the Dow and the S&P 500 reached their best closing levels in nearly six months.
RTT – Top Story

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Air France-KLM Q4 Loss Narrows, Plans Higher Capacity; Stock Up

Shares of Air France-KLM Group were gaining around 4 percent in Paris trading after the airline reported Wednesday narrower net loss in its fourth quarter with improved revenues. For fiscal 2019, Air France-KLM Group plans to selectively grow capacity for the Passenger network by 2 percent to 3 percent compared to 2018. The company also said it will pursue initiatives to reduce unit costs.
RTT – Earnings

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New model mimics persistent interneuron loss seen in prematurity

Research-clinicians created a novel preclinical model that mimics the persistent interneuron loss seen in preterm human infants, identifying interneuron subtypes that could become future therapeutic targets to prevent or lessen neurodevelopmental risks.
Infant and Preschool Learning News — ScienceDaily

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CORRECTED-UPDATE 1-Spotify posts surprise profit in Q4, sees loss in 2019

Spotify, the world’s most popular
paid music streaming service, reported an unexpected
fourth-quarter operating profit on Wednesday and sales growth
matching expectations, but it said it sees a loss of 200-360
million euros in 2019.


Reuters: Company News

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Anne Hathaway Says Her Dramatic Weight Loss For ‘Les Misérables’ Made Her ‘Really Sick’ | PeopleTV

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http://www.acrx.org -As millions of Americans strive to deal with the economic downturn,loss of jobs,foreclosures,high cost of gas,and the rising cost of prescription drug cost. Charles Myrick ,the President of American Consultants Rx, announced the re-release of the American Consultants Rx community service project which consist of millions of free discount prescription cards being donated to thousands of not for profits,hospitals,schools,churches,etc. in an effort to assist the uninsured,under insured,and seniors deal with the high cost of prescription drugs.-American Consultants Rx -Pharmacy Discount Network News

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The shutdown cost the economy $11 billion – including a permanent $3 billion loss, government says

Overall, the CBO projected economic growth will slow this year to 2.3 percent, compared with the 3.1 percent rate last year, as the benefits of the new tax law begin to fade.
Economy

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It may be possible to reverse memory loss caused by Alzheimer’s

Alzheimer’s disease is infamous for its devastating impact on memory, bringing significant mental and emotional stress to patients and their families. But scientists at the University of Buffalo believe they’re one step closer to reversing memory loss. Research published Wednesday in the journal Brain shows a possible solution by focusing on the emerging field of…
Living | New York Post

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As obesity rates in America soar, new weight loss drugs are in the offing that offer hope

There are several promising drug candidates to combat obesity, one of America's biggest diseases and contributors to mortality. Still, doctors have been slow to call obesity a disease, and insurance coverage remains skimpy.
Health and Science

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Broncos Face Major Questions Throughout Franchise After Dismaying Loss to Raiders

Vance Joseph and Case Keenum haven’t done much to improve their standing with the Broncos thanks to a December that has seen the team lose three straight games, including Monday night’s embarrassment to the Raiders. 

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Redskins routed by Giants, 40-16, as most fans leave at halftime of embarrassing home loss

Washington trailed 34-0 after two quarters in a loss that effectively ended its playoff hopes. Josh Johnson replaced Mark Sanchez and produces two late scoring drives.
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Beware Of Natural Supplements For Sex Gain And Weight Loss

Prescription pill bottle spilling pills on to surface isolated on a white background.

Many consumers consider dietary supplements to be natural and, therefore, safe. In fact, the Council for Responsible Nutrition reported in 2017 that 87 percent of U.S. consumers have confidence that dietary supplements, such as vitamins, minerals, herbs, botanicals, oils, microbiome bacteria and amino acids, are safe and effective. Unfortunately, their confidence may be misplaced when it comes to supplements for male sexual dysfunction and weight loss.

According to the Food and Drug Administration, 776 dietary supplement products from 146 different manufacturers sold between 2007 and 2016 contained synthetic/prescription drugs. Most of these products are marketed for just two conditions, sexual enhancement (45.5 percent) or weight loss (40.9 percent). Most recently, on Nov. 30, 2018, the FDA advised consumers not to purchase a product called Willy Go Wild, available online and in some retail stores because the product includes hidden prescription drugs.

Why does this matter?

As a pharmacist and dietary supplement researcher, I’m concerned about the hidden inclusion of these prescription drugs in supplements. It increases the risk of patient harm, and it allows people to attribute the benefits and harms they experience to an herb rather than to the true culprit – the added drug. This makes it harder for doctors and pharmacists to decipher in what types of patients these natural therapies could be used and in whom they should be avoided.

Risky sex enhancement pills

It is considered malpractice for pharmacists to fill prescriptions for erectile dysfunction (ED) drugs like Viagra, Levitra or Cialis if patients are taking nitrate drugs, such as nitroglycerin pills or spray or isosorbide mono/dinitrate. These nitrate drugs are often used to treat chest pain or heart failure. Combining them with a drug to treat ED; as the FDA said the makers of Willy Go Wild did, can cause a patient’s blood pressure to drop precipitously. This in turn can lead to hospitalization or death.

Some patients taking nitrate drugs, who cannot safely take one of the ED drugs, have turned instead to so-called natural products. Had they bought one of the 353 tainted products, they would have gotten the same active ingredients nonetheless.

In addition, prescription erectile dysfunction drugs can cause priapism, a medical emergency where the penis can be irreparably damaged. The higher the dose consumed, the greater the risk. So imagine you want to enhance your prescription erectile dysfunction drug with an herbal remedy only to find out you were getting a prescription drug’s active ingredient instead. There are cases of priapism with herbal sexual dysfunction medications.

ED drugs and antidepressants

Some other dietary supplement products for male enhancement added a drug called daptoxetine. The FDA has not approved it for any reason, including sexual dysfunction. People on other serotonin-enhancing drugs for depression or intestinal issues are more likely to end up with a condition called serotonin syndromewhen inadvertently exposed to this undisclosed drug. Serotonin syndrome is a life-threatening problem with high body temperatures, muscle stiffness, seizures and kidney damage.

Sibutramine, an appetite suppressant, was removed from the U.S. market by the FDA in 2010 because its use increases the risk of heart attacks and strokes. However, 269 dietary supplement products touted for weight loss contained sibutramine, and others contained the stimulants ephedrine and fenfluramine.

Ephedrine, a stimulant, was banned in the U.S. because it also increased cardiovascular riskFenfluramine, an amphetamine derivative, was combined with phentermine in the popular “fen-phen” diet that was banned after numerous cases of pulmonary hypertension, heart valve damage and heart failure occurred.

Still other dietary supplement products for weight loss contained the laxative phenolphthalein or prescription diuretics. Phenolphthalein is no longer used as a laxative in the U.S. because it may cause cancer and hurt fetuses. Laxatives and diuretics only cause weight loss through diarrhea or loss of water weight. They do not result in fat loss. They can cause dangerously low blood pressure and low blood potassium concentrations.

A study in the New England Journal of Medicine in 2015 estimated that dietary supplements led to 23,000 emergency department visits and over 2,000 hospitalizations a year. Weight loss products or those related to increased energy also caused 72 percent of supplement-related adverse events, including palpitations, chest pain or racing heart rate. I suspect the predominance of deliberate synthetic drug tainting of these dietary supplements might explain some of these findings.

How can you protect yourself?

The FDA does not approve dietary supplements, and in many ways you are on your own. The Dietary Supplement Health and Education Act (DSHEA) of 1994 created a new category of health product. As long as the product contains natural ingredients intended to promote or support health and not to diagnose, cure, treat, or prevent any disease, it qualifies as a dietary supplement. Under DSHEA, the FDA has to prove risk to human health before removing these products from the U.S. market.

The FDA, however, does have an ongoing list of products in which they have detected synthetic or prescription drugs, and you can check that out. If the product you have purchased is on that list, don’t use it. On Nov. 20, 2018, two dietary supplements for pain or drug addiction were found to be tainted with tianeptine, an antidepressant drug that is not FDA-approved for use in the U.S. market. If your product is not on that list, however, it doesn’t guarantee lack of tainting. The FDA simply does not have the resources to check the tens of thousands of dietary supplements on U.S. shelves.

Independent laboratory verification from the United States Pharmacopeia (USP) can help assure that the vitamin or herb specified on the label is in the bottle and that the product has a low risk of microbe, heavy metal or PCB contamination. Unfortunately, USP does not routinely test dietary supplements for synthetic or prescription drug tainting.

ConsumerLab.com does not usually test for prescription drug tainting during their product verification either. However, for sexual dysfunction drugs, ConsumerLab.com did test for prescription drug tainting.

Beware of dietary supplements manufactured in Asia, because they are more likely to be contaminated and tainted according to the FDA. Also, ethnically diverse, non-English speaking and poor people are more likely to come across tainted dietary supplements because they shop for these products at ethnic stores, flea markets, swap meets or online. Buying from reputable brands in reputable stores or websites might reduce the risk. Finally, don’t believe miraculous claims of effectiveness, especially if the only data to back it up comes from testimonials.

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Life & Style – Black America Web

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Hit by Fraud, Venmo Suffered a Big Loss and Shut Down Features, Report Says

Fraud hit Venmo hard in early 2018, leading the PayPal division for peer-to-peer payments to take an unexpectedly large loss due to fraudulent transactions and to shut down some of its features, according to a Wall Street Journal report.

Losses weighed in 40% higher than budgeted, at $ 40 million for the first quarter of 2018. That was reportedly 0.40% of volume, instead of an anticipated 0.24%.

In response, the company limited and shut down certain features, while blacklisting tens of thousands of accounts. This included pausing an instant-deposit feature, which allowed transfer of funds in a Venmo account to a bank account in as little as 30 minutes for $ 0.25. The feature returned later in the year with a 1% transaction fee.

Venmo also stopped allowing transactions from its Web site, requiring all payments to happen via its app. While 98% of users relied on the app already and only 2% used the Web site for transfers, 15% of net losses occurred via the Web site.

The Journal wasn’t able to determine what led to the elevated fraud. Venmo didn’t reply to a request for comment from Fortune.

The company has had few revenue sources in the past and has taken losses on operations since its start. However, it’s slowly shifting into more fee-based services, including letting customers pay for Uber and other services directly from their account balance.

Venmo is one of several companies contending for a vast market of money transfers between people for casual expenses like splitting the cost of a meal to much larger expenses like rent. Competitors include Zelle, run by a consortium of 30 major U.S. banks, and Square Cash, a system operated by the credit-card processing company Square.

Zelle handled $ 28 billion in transfers in the second quarter of 2018. Venmo managed about half that, or $ 14 billion, in the same period. Zelle has an estimated 23 million U.S. users, and Venmo about 27 million.

Fortune

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http://www.acrx.org -As millions of Americans strive to deal with the economic downturn,loss of jobs,foreclosures,high cost of gas,and the rising cost of prescription drug cost. Charles Myrick ,the President of American Consultants Rx, announced the re-release of the American Consultants Rx community service project which consist of millions of free discount prescription cards being donated to thousands of not for profits,hospitals,schools,churches,etc. in an effort to assist the uninsured,under insured,and seniors deal with the high cost of prescription drugs.-American Consultants Rx -Pharmacy Discount Network News

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I’m A Celeb’s Emily Atack boasts about weight loss after living off rations for seven days in the jungle

EMILY Atack boasted she’d lost weight in I’m A Celebrity after living off rations for a week.

The 28-year-old star pulled up her top and showed off her baggy trousers as she admired her slimmer stomach and extra wriggle room – seven days after entering the jungle.

Im a celeb
Emily Atack told the camp she has lost weight after living off rice and beans for a week in Im A Celeb
Rex Features
Emily Atack
Emily made fans laugh when she pulled up her top and showed off her belly on I’m A Celeb
Rex Features

Emily said to Fleur East and John Barrowman: “These were tight when I came in here. I just want to lose a bit of weight so that when I get home and it’s Christmas I have a bit of room and can put it back on again.

She added: “I love food so much, I love cheese and champagne and salads, fries, yum.”

John reassured The Inbetweeners star that she looked great and got the camp mates salivating with a cheese dip recipe.

Emily Atack
Emily was proud of her the weight loss
Rex Features

He said: “Just chuck a Camembert in the oven and rub your face in it when it comes out, a cheese facial.”
But Noel got frisky and added: “And get someone you love to lick it off.”

Emily had fans in a lather earlier this week when she stripped off with Fleur and Sair Khan for a jungle shower.

She wasn’t the only star to enjoy their first jungle soak, with Harry Redknapp whipping his kit off.


Love I’m A Celeb? Play our new game The Jungle now – win daily prizes and a holiday worth £5K


Rex Features

I’m A Celeb’s Emily Atack stunned in a blue bikini tonight as she hit the camp shower for the first time[/caption]

Rex Features

The actress looked great in the tasselled two-piece, beaming as she scrubbed herself down[/caption]

Rex Features

Sair Khan opted for a stylish black set in the tub[/caption]

She managed to get clean after a long day of trials
Rex Features
Rex Features
Fleur paddled in the water and cooled off as Emily and Rita Simons also made the most of bath time
Rex Features

Rex Features

Harry Redknapp whipped his kit off[/caption]

The football manager enjoyed a thorough wash in his blue swimshorts, coordinating nicely with Emily.

Fleur East brought the sunshine with her yellow bikini, while Sair Khan opted for a stylish black set.

The shower scenes go down a treat with fans each year and tonight was no exception.

One viewer who won’t be so keen on seeing Harry shower, though, is his former Liverpool and England midfielder son Jamie, 45, who previously said: “Dad hasn’t really got any phobias, to be honest.Emily Atack

Emily Atack admitted to The Sun that she is looking for love


“As a kid he was never worried about spiders. I’m worried about him with the shower scene in his pants!

“I hope he finds a mate in there because from people I’ve spoken to the hardest things are lack of food, but he doesn’t eat a lot my dad so that’s gonna help him, and secondly it’s the boredom factor, there’s no racing channel for him to watch.”

Listen to new podcast Jungle VIP, talkRADIO’s cheeky, no-holds-barred take on the action Down Under. Hosted by Jamie East with daily guests, including former campmates and celeb reality TV fans the gang will dish the dirt on the REAL behind-the-scenes gossip. Read more here.

TV and Showbiz – latest celebrity news, gossip, photos, TV and film reviews | The Sun

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Wisconsin’s Loss to Minnesota Seals Badgers as 2018’s Biggest Disappointment

Wisconsin faces major questions this offseason about its status in the Big Ten West after a catastrophic campaign that began with such high expectations. 

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British Land Slips To Loss In H1 – Quick Facts

British Land Co Plc. (BRLAF, BTLCY, BLND.L) reported Thursday that its IFRS loss before tax for the six months ended 30 September 2018 was 42 million pounds, compared to profit of 238 million pounds in the year-ago period. IFRS basic loss per share for the period was 4.9 pence, compared to earnings of 23.2 pence last year.
RTT – Earnings

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Uber posts $1B quarterly loss as bookings growth slows

Uber Technologies said on Wednesday that growth in bookings for its ride-hailing and delivery services rose 6 percent in the latest quarter, the third quarter in a row that growth has remained in the single digits after double-digit growth for all of last year. The San Francisco-based firm lost $ 1.07 billion for the three months…
Business | New York Post

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‘Sisters in Loss’ Helps Black Women Cope With Miscarriage and Infertility

In November 2012, when Virginia native Erica M. McAfee lost her son at birth, she felt the loneliness, shame, and isolation that comes after the death of a child.

“I was broken and empty and my immediate family couldn’t console me,” said McAfee. “No one in my circle of friends was pregnant yet, or had an infant loss experience. I turned to the Internet to find stories and I found many women online who had experienced pregnancy loss, but they didn’t look like me. In 2014, I had Maxwell, my rainbow baby (a baby that is born after a miscarriage, stillbirth, or loss of an infant). I started to share more of our story about how we almost lost our lives during birth due to a placenta abruption. My son was diagnosed with Cerebral Palsy so we moved closer to our family to have support. During my 4-hour commute to work, I fell in love with listening to podcasts. My husband and I knew we wanted to grow our family, and I wanted to hear more stories black women struggling through grief, loss, and infertility.”

On a mission to turn her pain into purpose, McAfee became a Pregnancy Loss Grief Coach, and Birth & Bereavement Doula. In 2017, she launched Sisters in Loss L.L.C.—a coaching program, podcast community of 10,000 and series of resources, and retreats to help black women heal, gain clarity, and find an empowering path forward after loss.

“At first it was difficult to get black women to share their experiences,” said McAfee. Then, as more celebrities and influencers like Beyoncé, Serena Williams, Remy Ma, and Kandi, and Eudoxie began sharing their journeys, black women started saying yes I experienced that as well. Can I share my story? Since March 2018, the podcast is 6 months booked out because of the many women willing to share their stories and journey’s to motherhood.” 

Hiding in Plain Sight

Here’s a harsh reality. More than 6 million women and couples suffer from infertility, and black women are 3-4 times more likely to die from pregnancy-related complications and infant death than white women according to the CDC. Yet, every day millions of black women show up for work suffering in silence, dealing with cultural shame and age-related pressures of society.

Recently, during an interview with Good Morning America, former first lady Michelle Obama revealed 20 years ago she suffered a miscarriage before having daughters Malia and Sasha. “I felt like I failed because I didn’t know how common miscarriages were because we don’t talk about them,” Obama said. “We sit in our own pain, thinking that somehow we’re broken. I think it’s important to talk to young mothers about the fact that miscarriages happen.” Ultimately, she and her husband, former President Barack Obama used IVF to conceive their daughters.

Black Women Cope With Miscarriage and Infertility

Erica M/ McAfee

“Not many black women are sharing their stories and journey’s good or bad about motherhood,” said McAfee. In our community, we keep these “secrets” to ourselves, versus sharing it to free others from the shame.” McAfee also shared a few misconceptions she often hears:

-Black women are very fertile and can get pregnant as soon as we stop birth control or contraceptives.

-If you already have a child that you shouldn’t experience infertility.

Turning Pain into Purpose

Beyond creating safe and supportive spaces for black women, Sisters and Loss are working to see legislative changes, for more research around black women mortality and infant outcomes.

“I’m working on this by using my podcast programming and platform to highlight specific issues that will affect us from a legislative perspective,” said McAfee. This includes advocacy at the state level and federal level to pass bills to provide more substantial testing for fertility and universal health care for all, paid in full IVF treatments and midwives and Doula services covered by insurance. Also, out of pocket expenses for fertility treatments is why many black women and couples do not pursue this path to motherhood. We simply don’t have tens of thousands of dollars in disposable income to spend on one treatment of IVF ($ 30K), and if that treatment isn’t successful it can be discouraging and depressing.”

Watching Michele Obama share her story gave McAfee more fuel to turn her message into a movement.

“Our Forever FLOTUS freed us with her voice by saying she felt alone, felt unworthy, and was in pain,” said McAfee. “When black women share their stories, they invite others to share and shatter the stigma around miscarriage and infertility and they will change the world. I’m proud to be a bridge and connect women in a sisterhood that is rooted in our faith in God and faith in ourselves to push past grief to achieve their dreams and career goals.  I love coaching clients on their journey’s to motherhood and helping them bring a happy and healthy baby home from the hospital. This work continues to inspire me because of the messages I receive daily thanking me for giving black women a voice and a platform to share their stories. “

The post ‘Sisters in Loss’ Helps Black Women Cope With Miscarriage and Infertility appeared first on Black Enterprise.

Lifestyle | Black Enterprise

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Body Goals: Jazmine Sullivan Shows Off Weight Loss On Instagram

ESSENCE Best In Black Beauty Awards Carnival

Source: D Dipasupil / Getty

Listen…Jazmine Sullivan is back…and looking like a snack!

The 31-year-old has been on Instagram showing off her svelte snatched body after losing what looks like more than 70 pounds.

Here’s the “Need U Bad” singer slaying in this royal blue suit!

Instagram Photo

 

Looking like Nicki Minaj’s twin, here’s another amazing picture of her back in September looking flawless in a black and white patterned suit. She has definitely been working out.

Instagram Photo

 

YAAASSSS!

Instagram Photo

Fans have been flocking to social media to show the songtress some love and congratulate on all of her hard weight-loss work.

It’s pretty obvious that Jaz has been hitting the gym and eating healthier for the past year. According to a June 2018 Media TakeOut post, Jazmine weighed around 190 pounds. But thanks to her intensive weight loss regimen, she’s dropped 60 pounds.

Listen, we love Jazmine at any size, we’re just happy that she’s happy!


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Life & Style – Black America Web

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Sing Away Parkinson’s, Dark Roast Coffee For Alzheimer’s, New Gene & Hair Loss

He who sings, frightens away his ills, said Spanish writer Miguel de Cervantes. That’s exactly what a new study, conducted by Iowa State University researchers, has found. In this week’s “Did you know” column, we are presenting interesting findings about the relationship between music therapy and Parkinson’s, discovery of a new gene that is responsible for a rare form of hair loss.
RTT – Top Story

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Gastric Bypass Surgery Associated With Greater Weight Loss in Adults Than Other Procedures

SEATTLE — Adults with severe obesity had greater initial and sustained weight loss with gastric bypass surgery than either sleeve gastrectomy or adjustable gastric banding, according to a new published today in the Annals of Internal Medicine.

This is the largest long-term study of bariatric surgery to date. It included more than 46,000 patients at 41 participating health systems in 11 Clinical Data Research Networks nationwide, thanks to its use of a large new resource called PCORnet®, the National Patient-Centered Clinical Research Network.

Bariatric surgeons can use various operations to help people lose weight by making changes to their digestive system. This study did a head-to-head comparison of 1-, 3- and 5-year results from the three most commonly performed weight-loss operations: gastric bypass, sleeve gastrectomy and adjustable gastric banding. 

The findings are important because severe obesity — a body mass index (or BMI) of at least 35 kg/m2 — affects more than 15 percent of U.S. adults, according to the National Health and Nutrition Examination Survey. National Institutes of Health guidelines consider people with a BMI of 40 kg/m2, or at least 35 kg/m2 for people with diabetes or other obesity-related diseases, eligible for bariatric surgery.

“Bariatric surgery is widely considered the most effective way to treat severe obesity and induce long-term weight loss,” said first author David Arterburn, MD, MPH, an internist and senior investigator at Kaiser Permanente Washington Health Research Institute. “We wondered about sleeve gastrectomy, which has quickly become the most commonly performed bariatric procedure in the United States. Because it’s the newest — introduced less than a decade ago — less evidence has been available to compare it against the longstanding gastric bypass and adjustable gastric band.”

The investigators found that:

  • People who had gastric bypass surgery had lost 31 percent of their weight at the first year and maintained 26 percent of their loss at 5 years.
  • People who had sleeve gastrectomy had lost 25 percent of their pre-surgery body weight at 1 year and maintained 19 percent weight loss at 5 years.
  • That translates into a 19-pound difference in weight loss between gastric bypass and sleeve gastrectomy at 5 years for the average person in this study, who weighed 277 pounds before surgery.
  • By contrast, adjustable gastric banding was much less effective for losing weight and keeping it off, with 14 percent and 12 percent of weight lost at 1 and 5 years, respectively. Gastric banding used to be the most commonly performed bariatric procedure, but it now represents just 10 percent of bariatric procedures.

“These findings give strong evidence that bypass and sleeve are effective for lasting weight loss for adults with severe obesity,” said Kathleen M. McTigue, MD, MPH, MS, another study leader and an associate professor of medicine and epidemiology at the University of Pittsburgh. “We hope this helps people to make more informed decisions about their care, as they talk with their health care providers about the respective benefits and risks of the most common weight-loss procedures.”

Members of the same PCORnet® Bariatric Study Collaborative team had found similar results in teenagers.

Because of the large sample size, the researchers could examine subgroups of people to assess whether certain characteristics improved or worsened their chance of weight loss success. They found that men, African-Americans, Hispanics, people age 65 and older, and people with diabetes or lower BMIs (less than 50) tended to lose less weight than did other people in the study. But these differences between patient groups were small — less than 3 percent differences in weight lost at 1, 3 and 5 years across groups — which was much less than the differences between the procedures. For instance, the difference between weight lost with gastric bypass and sleeve gastrectomy was 6 percent at 1 year and 7 percent at 5 years. 

The 30-day risk of major adverse events, such as a prolonged hospitalization or another operation, were generally low across all three procedures. Sleeve gastrectomy had the lowest rate of major adverse events (2.6 percent), followed by gastric banding (2.9 percent), and then gastric bypass (5.0 percent).

The new results are among the first to be produced using the resources of PCORnet®, an innovative initiative funded by the Patient-Centered Outcomes Research Institute (or PCORI). PCORnet® is designed to produce clinical insights faster and less expensively than traditional clinical studies. It involves multiple individual networks that together represent more than 100 million patients.

The network securely collects health information during routine care — not including data that could help identify individuals — to produce real-world evidence with outcomes that matter to patients, who are full partners in this research.

“Our patients and providers were critical to the success of this study,” said Karen J. Coleman, PhD, MS, another study leader and a research scientist at Kaiser Permanente in Southern California’s Department of Research & Evaluation in Pasadena. “They helped us craft the question, pick the variables to study, interpret the findings and present the results. We could never have done such a comprehensive study without their partnership.”

“We helped the group think through the most important questions for patients, like risks and safety concerns,” said the Rev. Neely Williams, MDiv, a patient-principal investigator on the study and the CEO of the Community Partners’ Network in Nashville. “We also explored how best to share evidence with patients.”

The PCORnet® Bariatric Study Collaborative team is continuing to examine the outcomes of different types of weight-loss surgery for longer-term safety as well as outcomes in people with diabetes.

This PCORnet® study, registered at ClinicalTrials.gov (NCT02741674), was funded by PCORI through PCORI Award OBS-1505-30683.

For the PCORnet® Bariatric Study Collaborative, the other coauthors are Robert Wellman, MS, R. Yates Coley, PhD, Andrea J. Cook, PhD, Jane Anau, and Roy Pardee, JD, MA, of Kaiser Permanente Washington Health Research Institute; Sameer Murali, MD, of Kaiser Permanente in Southern California’s Department of Research and Evaluation in Pasadena; Sengwee Toh, ScD, Jessica Sturtevant, MS, and Casie Horgan, MPH, of Harvard Medical School’s Department of Population Medicine and Harvard Pilgrim Health Care Institute in Boston; Ana Emiliano, M.D., of Rockefeller University in New York; Steven R. Smith, MD, of Florida Hospital’s The Translational Research Institute for Metabolism and Diabetes in Orlando; Andrew O. Odegaard, PhD, MPH, of the University of California, Irvine School of Medicine’s Department of Epidemiology; Cheri Janning RN, BSN, MS, of Duke Clinical & Translational Science Institute in Durham, NC; Anita Courcoulas, MD, MPH, of the University of Pittsburgh’s Department of Surgery.


About Kaiser Permanente Washington Health Research Institute
Kaiser Permanente Washington Health Research Institute improves the health and health care of Kaiser Permanente members and the public. The Institute has conducted nonproprietary public-interest research on preventing, diagnosing, and treating major health problems since 1983. Government and private research grants provide our main funding. Follow KPWHRI research on TwitterFacebookLinkedIn, or YouTube. For more information, go to: www.kpwashingtonresearch.org.

About Kaiser Permanente
Kaiser Permanente is committed to helping shape the future of health care. We are recognized as one of America’s leading health care providers and not-for-profit health plans. Founded in 1945, Kaiser Permanente has a mission to provide high-quality, affordable health care services and to improve the health of our members and the communities we serve. We currently serve more than 12.2 million members in eight states and the District of Columbia. Care for members and patients is focused on their total health and guided by their personal Permanente Medical Group physicians, specialists and team of caregivers. Our expert and caring medical teams are empowered and supported by industry-leading technology advances and tools for health promotion, disease prevention, state-of-the-art care delivery and world-class chronic disease management. Kaiser Permanente is dedicated to care innovations, clinical research, health education and the support of community health. For more information, go to: kp.org/share.

The post Gastric Bypass Surgery Associated With Greater Weight Loss in Adults Than Other Procedures appeared first on Kaiser Permanente.

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NEW PARENT ESSENTIAL UPDATE:

Loss of first baby tooth a positive experience for children

Scared, ashamed, happy or proud — how do children feel when they lose their first baby tooth? Scientists have now found that children’s feelings are predominantly positive. The study also reveals that previous visits to the dentist’s as well as parental background and level of education affect how children experience the loss of their first tooth.
Child Development News — ScienceDaily

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Mo’Nique Is Living Her Best Weight Loss Life [WATCH]

BET Hip Hop Awards 2010 - Show

Source: Taylor Hill / Getty

Mo’Nique is done with ranting about those who have done her wrong and the craziness of people in Hollywood – for now.

She’s focusing lately on showing off the results of her estimated 100 pound plus weight loss. 

The Oscar-winner recently shared on a video showing off her super-snatched waist..and it was everything.

She let her fans get a little peek of her at a recent photo shoot rocking a pair of curve-hugging jeans and a cinched waist poppin’ to Cardi B’s “Bodak Yellow. ” The 50-year-old also showed some love to her fitness trainer Dwight Holt, Jr., for helping her dance off the pounds.

“CARDI B, baby you will get a photo shoot going. DANCING MY POUNDS OFF. WHAT A TEAM,” she wrote.

 

Earlier this year, Mo celebrated weighing under 200 pounds for the first time since high school.

“I said that I would share this new journey with y’all on the weight loss and getting healthy,” the comedian said in a video she posted on Instagram.

“Today was the first time in my adult life that I’ve been under 200 pounds, so I wanted to let you all know it’s possible and you can do it and we can get there.”

She added that she achieved this weight loss without having to go under the knife or falling for any diet fads.

“For me it was no surgery, no prepackaged foods, not listening to no spokespeople saying ‘it’s easy and you can do it.’”

“It was just putting in the work and not giving up on me … it’s called giving yourself a chance to live the best life you can live.”

Instagram Photo

Clearly, all this hard work has paid off:

Instagram Photo

What do you think of Mo’s weight loss and new body?


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Giants WR Sterling Shepard explains his sideline outburst during Sunday’s loss to Panthers

Sterling Shepard said a combination of stress in his personal life and the frustration of losing led to his uncharacteristic outburst on the sidelines during Sunday’s second half in Carolina.

And on Tuesday Shepard said it won’t happen again.

“It was just built-up frustration,” Shepard said. “I…

Sports – New York Daily News

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